| Port Neches to Southern Pines (North Carolina) | 918.92 mi (1,478.85 km) |
| Port Neches to Southfield (Michigan) | 1,047.18 mi (1,685.27 km) |
| Port Neches to Southgate (Michigan) | 1,034.17 mi (1,664.34 km) |
| Port Neches to Southlake (Texas) | 279.25 mi (449.41 km) |
| Port Neches to Spanaway (Washington) | 1,922.89 mi (3,094.59 km) |
| Port Neches to Spanish Fork (Utah) | 1,217.79 mi (1,959.84 km) |
| Port Neches to Spanish Lake (Missouri) | 644.91 mi (1,037.88 km) |
| Port Neches to Spanish Springs (Nevada) | 1,597.57 mi (2,571.04 km) |
| Port Neches to Sparks (Nevada) | 1,598.30 mi (2,572.22 km) |
| Port Neches to Spartanburg (South Carolina) | 779.56 mi (1,254.59 km) |
| Port Neches to Spearfish (South Dakota) | 1,138.37 mi (1,832.03 km) |
| Port Neches to Speedway (Indiana) | 805.73 mi (1,296.70 km) |
| Port Neches to Spencer (Iowa) | 912.41 mi (1,468.39 km) |
| Port Neches to Spokane (Washington) | 1,745.30 mi (2,808.79 km) |
| Port Neches to Spokane Valley (Washington) | 1,737.66 mi (2,796.49 km) |
