| Portalegre to Selargius | 885.29 mi (1,424.74 km) |
| Portalegre to Selvazzano Dentro | 1,062.85 mi (1,710.50 km) |
| Portalegre to Senago | 945.85 mi (1,522.19 km) |
| Portalegre to Senigallia | 1,106.64 mi (1,780.97 km) |
| Portalegre to Seravezza | 964.55 mi (1,552.30 km) |
| Portalegre to Seregno | 950.53 mi (1,529.73 km) |
| Portalegre to Seriate | 974.72 mi (1,568.65 km) |
| Portalegre to Sermoneta | 1,081.31 mi (1,740.20 km) |
| Portalegre to Serramanna | 871.53 mi (1,402.60 km) |
| Portalegre to Serravalle Pistoiese | 992.10 mi (1,596.63 km) |
| Portalegre to Sessa Aurunca | 1,130.34 mi (1,819.10 km) |
| Portalegre to Sesto Calende | 927.38 mi (1,492.47 km) |
| Portalegre to Sesto Fiorentino | 1,009.01 mi (1,623.85 km) |
| Portalegre to Sesto San Giovanni | 949.11 mi (1,527.44 km) |
| Portalegre to Sestri Levante | 929.02 mi (1,495.12 km) |
