| Portalegre to Santiago do Cacem | 113.40 mi (182.50 km) |
| Portalegre to Santo Andre | 113.27 mi (182.29 km) |
| Portalegre to Santo Tirso | 149.91 mi (241.25 km) |
| Portalegre to Sao Bras de Alportel | 151.83 mi (244.35 km) |
| Portalegre to Sao Felix da Marinha | 134.66 mi (216.71 km) |
| Portalegre to Sao Joao da Madeira | 123.02 mi (197.99 km) |
| Portalegre to Sao Joao de Ver | 128.01 mi (206.01 km) |
| Portalegre to Sao Mamede de Infesta | 144.30 mi (232.24 km) |
| Portalegre to Sao Pedro do Sul | 104.83 mi (168.71 km) |
| Portalegre to Satao | 99.30 mi (159.81 km) |
| Portalegre to Seia | 77.86 mi (125.30 km) |
| Portalegre to Senhora da Hora | 144.63 mi (232.75 km) |
| Portalegre to Serpa | 95.30 mi (153.38 km) |
| Portalegre to Serta | 49.40 mi (79.49 km) |
| Portalegre to Sesimbra | 108.77 mi (175.05 km) |
