| Portes-les-Valence to Santeramo in Colle | 664.06 mi (1,068.71 km) |
| Portes-les-Valence to Santo Stefano di Magra | 253.00 mi (407.17 km) |
| Portes-les-Valence to Santo Stino di Livenza | 383.86 mi (617.76 km) |
| Portes-les-Valence to Sarezzo | 264.35 mi (425.43 km) |
| Portes-les-Valence to Sarno | 566.92 mi (912.37 km) |
| Portes-les-Valence to Saronno | 208.92 mi (336.23 km) |
| Portes-les-Valence to Sarzana | 255.94 mi (411.90 km) |
| Portes-les-Valence to Sassari | 341.88 mi (550.20 km) |
| Portes-les-Valence to Sasso Marconi | 314.98 mi (506.91 km) |
| Portes-les-Valence to Sassuolo | 290.93 mi (468.21 km) |
| Portes-les-Valence to Sava | 714.18 mi (1,149.37 km) |
| Portes-les-Valence to Saviano | 558.79 mi (899.29 km) |
| Portes-les-Valence to Savigliano | 136.12 mi (219.07 km) |
| Portes-les-Valence to Savignano sul Panaro | 303.61 mi (488.62 km) |
| Portes-les-Valence to Savignano sul Rubicone | 374.37 mi (602.49 km) |
