| Portes-les-Valence to Settimo Torinese | 142.33 mi (229.06 km) |
| Portes-les-Valence to Seveso | 213.93 mi (344.28 km) |
| Portes-les-Valence to Sezze | 473.56 mi (762.11 km) |
| Portes-les-Valence to Siano | 570.87 mi (918.72 km) |
| Portes-les-Valence to Siena | 337.73 mi (543.53 km) |
| Portes-les-Valence to Signa | 316.60 mi (509.52 km) |
| Portes-les-Valence to Silea | 364.73 mi (586.98 km) |
| Portes-les-Valence to Silvi Paese | 488.27 mi (785.79 km) |
| Portes-les-Valence to Sinalunga | 359.13 mi (577.96 km) |
| Portes-les-Valence to Siniscola | 384.66 mi (619.05 km) |
| Portes-les-Valence to Sinnai | 444.10 mi (714.70 km) |
| Portes-les-Valence to Siracusa | 764.13 mi (1,229.75 km) |
| Portes-les-Valence to Solaro | 210.97 mi (339.53 km) |
| Portes-les-Valence to Soliera | 296.57 mi (477.28 km) |
| Portes-les-Valence to Solofra | 576.59 mi (927.93 km) |
