| Poughkeepsie to Elyria (Ohio) | 423.73 mi (681.93 km) |
| Poughkeepsie to Emeryville (California) | 2,549.00 mi (4,102.22 km) |
| Poughkeepsie to Emmaus (Pennsylvania) | 114.70 mi (184.60 km) |
| Poughkeepsie to Emporia (Kansas) | 1,196.21 mi (1,925.11 km) |
| Poughkeepsie to Encinitas (California) | 2,426.51 mi (3,905.10 km) |
| Poughkeepsie to Endicott (New York) | 113.66 mi (182.92 km) |
| Poughkeepsie to Endwell (New York) | 111.91 mi (180.11 km) |
| Poughkeepsie to Englewood (Colorado) | 1,625.67 mi (2,616.26 km) |
| Poughkeepsie to Englewood (Florida) | 1,123.86 mi (1,808.68 km) |
| Poughkeepsie to Englewood (New Jersey) | 55.57 mi (89.43 km) |
| Poughkeepsie to Englewood (Ohio) | 557.53 mi (897.26 km) |
| Poughkeepsie to Enid (Oklahoma) | 1,331.06 mi (2,142.13 km) |
| Poughkeepsie to Ennis (Texas) | 1,404.47 mi (2,260.28 km) |
| Poughkeepsie to Ensley (Florida) | 1,070.31 mi (1,722.50 km) |
| Poughkeepsie to Enterprise (Alabama) | 973.63 mi (1,566.90 km) |
