| Poughkeepsie to Orangeburg (South Carolina) | 681.92 mi (1,097.45 km) |
| Poughkeepsie to Orangevale (California) | 2,473.68 mi (3,981.01 km) |
| Poughkeepsie to Orchards (Washington) | 2,406.56 mi (3,872.98 km) |
| Poughkeepsie to Orcutt (California) | 2,534.38 mi (4,078.69 km) |
| Poughkeepsie to Oregon (Ohio) | 490.61 mi (789.56 km) |
| Poughkeepsie to Oregon (Wisconsin) | 793.77 mi (1,277.45 km) |
| Poughkeepsie to Oregon City (Oregon) | 2,414.28 mi (3,885.40 km) |
| Poughkeepsie to Orem (Utah) | 1,956.58 mi (3,148.81 km) |
| Poughkeepsie to Orinda (California) | 2,542.12 mi (4,091.15 km) |
| Poughkeepsie to Orland Park (Illinois) | 718.96 mi (1,157.05 km) |
| Poughkeepsie to Orlando (Florida) | 1,003.90 mi (1,615.62 km) |
| Poughkeepsie to Ormond Beach (Florida) | 946.08 mi (1,522.58 km) |
| Poughkeepsie to Oro Valley (Arizona) | 2,122.83 mi (3,416.36 km) |
| Poughkeepsie to Oroville (California) | 2,471.98 mi (3,978.26 km) |
| Poughkeepsie to Oshkosh (Wisconsin) | 757.67 mi (1,219.35 km) |
