| Poughkeepsie to Scottsboro (Alabama) | 818.04 mi (1,316.50 km) |
| Poughkeepsie to Scottsdale (Arizona) | 2,128.45 mi (3,425.40 km) |
| Poughkeepsie to Scranton (Pennsylvania) | 92.38 mi (148.66 km) |
| Poughkeepsie to Seabrook (Maryland) | 242.83 mi (390.79 km) |
| Poughkeepsie to Seabrook (Texas) | 1,444.54 mi (2,324.77 km) |
| Poughkeepsie to Seaford (New York) | 74.39 mi (119.73 km) |
| Poughkeepsie to Seagoville (Texas) | 1,387.63 mi (2,233.18 km) |
| Poughkeepsie to Seal Beach (California) | 2,446.52 mi (3,937.29 km) |
| Poughkeepsie to Searcy (Arkansas) | 1,059.12 mi (1,704.48 km) |
| Poughkeepsie to Seaside (California) | 2,556.79 mi (4,114.76 km) |
| Poughkeepsie to SeaTac (Washington) | 2,374.78 mi (3,821.85 km) |
| Poughkeepsie to Seattle (Washington) | 2,374.17 mi (3,820.86 km) |
| Poughkeepsie to Sebastian (Florida) | 1,030.10 mi (1,657.78 km) |
| Poughkeepsie to Sebring (Florida) | 1,070.62 mi (1,723.00 km) |
| Poughkeepsie to Secaucus (New Jersey) | 63.60 mi (102.35 km) |
