| Poughkeepsie to Security-Widefield (Colorado) | 1,628.45 mi (2,620.74 km) |
| Poughkeepsie to Sedalia (Missouri) | 1,037.57 mi (1,669.81 km) |
| Poughkeepsie to Sedro-Woolley (Washington) | 2,361.71 mi (3,800.81 km) |
| Poughkeepsie to Seguin (Texas) | 1,579.94 mi (2,542.67 km) |
| Poughkeepsie to Selden (New York) | 72.80 mi (117.16 km) |
| Poughkeepsie to Selma (Alabama) | 964.26 mi (1,551.83 km) |
| Poughkeepsie to Selma (California) | 2,445.41 mi (3,935.50 km) |
| Poughkeepsie to Selma (Texas) | 1,596.34 mi (2,569.06 km) |
| Poughkeepsie to Seminole (Florida) | 1,079.72 mi (1,737.64 km) |
| Poughkeepsie to Seven Hills (Ohio) | 401.39 mi (645.98 km) |
| Poughkeepsie to Seven Oaks (South Carolina) | 658.52 mi (1,059.78 km) |
| Poughkeepsie to Severn (Maryland) | 229.27 mi (368.97 km) |
| Poughkeepsie to Severna Park (Maryland) | 227.75 mi (366.53 km) |
| Poughkeepsie to Sevierville (Tennessee) | 655.73 mi (1,055.30 km) |
| Poughkeepsie to Seymour (Indiana) | 657.87 mi (1,058.74 km) |
