| Poughkeepsie to Seymour (Tennessee) | 664.62 mi (1,069.60 km) |
| Poughkeepsie to Shady Hills (Florida) | 1,038.52 mi (1,671.34 km) |
| Poughkeepsie to Shafter (California) | 2,454.15 mi (3,949.57 km) |
| Poughkeepsie to Shaker Heights (Ohio) | 394.41 mi (634.74 km) |
| Poughkeepsie to Shakopee (Minnesota) | 1,004.52 mi (1,616.62 km) |
| Poughkeepsie to Sharon (Pennsylvania) | 342.02 mi (550.43 km) |
| Poughkeepsie to Sharonville (Ohio) | 575.24 mi (925.76 km) |
| Poughkeepsie to Shasta Lake (California) | 2,486.69 mi (4,001.95 km) |
| Poughkeepsie to Shawnee (Kansas) | 1,112.34 mi (1,790.14 km) |
| Poughkeepsie to Shawnee (Oklahoma) | 1,315.60 mi (2,117.25 km) |
| Poughkeepsie to Sheboygan (Wisconsin) | 714.27 mi (1,149.50 km) |
| Poughkeepsie to Shelby (North Carolina) | 604.31 mi (972.55 km) |
| Poughkeepsie to Shelbyville (Indiana) | 639.03 mi (1,028.41 km) |
| Poughkeepsie to Shelbyville (Kentucky) | 644.99 mi (1,038.01 km) |
| Poughkeepsie to Shelbyville (Tennessee) | 799.46 mi (1,286.61 km) |
