| Poughkeepsie to Smyrna (Delaware) | 188.11 mi (302.74 km) |
| Poughkeepsie to Smyrna (Georgia) | 791.07 mi (1,273.11 km) |
| Poughkeepsie to Smyrna (Tennessee) | 784.21 mi (1,262.06 km) |
| Poughkeepsie to Snellville (Georgia) | 771.31 mi (1,241.31 km) |
| Poughkeepsie to Snoqualmie (Washington) | 2,352.80 mi (3,786.47 km) |
| Poughkeepsie to Snyder (Texas) | 1,601.21 mi (2,576.91 km) |
| Poughkeepsie to Socastee (South Carolina) | 618.98 mi (996.15 km) |
| Poughkeepsie to Socorro (Texas) | 1,908.42 mi (3,071.31 km) |
| Poughkeepsie to Soddy-Daisy (Tennessee) | 752.83 mi (1,211.56 km) |
| Poughkeepsie to Solana Beach (California) | 2,428.05 mi (3,907.57 km) |
| Poughkeepsie to Soledad (California) | 2,537.27 mi (4,083.33 km) |
| Poughkeepsie to Solon (Ohio) | 389.30 mi (626.52 km) |
| Poughkeepsie to Somers Point (New Jersey) | 168.22 mi (270.73 km) |
| Poughkeepsie to Somerset (Kentucky) | 653.03 mi (1,050.96 km) |
| Poughkeepsie to Somerset (New Jersey) | 87.37 mi (140.62 km) |
