| Poughkeepsie to Somersworth (New Hampshire) | 188.46 mi (303.30 km) |
| Poughkeepsie to Somerton (Arizona) | 2,308.62 mi (3,715.36 km) |
| Poughkeepsie to Somerville (Massachusetts) | 152.45 mi (245.35 km) |
| Poughkeepsie to Somerville (New Jersey) | 85.61 mi (137.77 km) |
| Poughkeepsie to Sonoma (California) | 2,546.07 mi (4,097.51 km) |
| Poughkeepsie to Soquel (California) | 2,553.30 mi (4,109.13 km) |
| Poughkeepsie to South Bend (Indiana) | 636.63 mi (1,024.55 km) |
| Poughkeepsie to South Bradenton (Florida) | 1,098.53 mi (1,767.92 km) |
| Poughkeepsie to South Burlington (Vermont) | 194.44 mi (312.92 km) |
| Poughkeepsie to South Charleston (West Virginia) | 472.75 mi (760.82 km) |
| Poughkeepsie to South Daytona (Florida) | 952.27 mi (1,532.54 km) |
| Poughkeepsie to South El Monte (California) | 2,436.41 mi (3,921.02 km) |
| Poughkeepsie to South Elgin (Illinois) | 740.23 mi (1,191.28 km) |
| Poughkeepsie to South Euclid (Ohio) | 392.84 mi (632.22 km) |
| Poughkeepsie to South Farmingdale (New York) | 71.89 mi (115.69 km) |
