| Poughkeepsie to Stephenville (Texas) | 1,485.97 mi (2,391.44 km) |
| Poughkeepsie to Sterling (Colorado) | 1,517.18 mi (2,441.67 km) |
| Poughkeepsie to Sterling (Illinois) | 812.06 mi (1,306.88 km) |
| Poughkeepsie to Sterling (Virginia) | 261.09 mi (420.19 km) |
| Poughkeepsie to Sterling Heights (Michigan) | 470.48 mi (757.16 km) |
| Poughkeepsie to Steubenville (Ohio) | 362.54 mi (583.45 km) |
| Poughkeepsie to Stevens Point (Wisconsin) | 810.86 mi (1,304.95 km) |
| Poughkeepsie to Stevenson Ranch (California) | 2,454.09 mi (3,949.47 km) |
| Poughkeepsie to Stillwater (Minnesota) | 975.22 mi (1,569.47 km) |
| Poughkeepsie to Stillwater (Oklahoma) | 1,298.13 mi (2,089.14 km) |
| Poughkeepsie to Stockbridge (Georgia) | 796.96 mi (1,282.59 km) |
| Poughkeepsie to Stockton (California) | 2,495.66 mi (4,016.37 km) |
| Poughkeepsie to Stone Ridge (Virginia) | 270.47 mi (435.28 km) |
| Poughkeepsie to Stonecrest (Georgia) | 785.26 mi (1,263.75 km) |
| Poughkeepsie to Stony Brook (New York) | 68.31 mi (109.94 km) |
