| Poughkeepsie to Storm Lake (Iowa) | 1,088.57 mi (1,751.89 km) |
| Poughkeepsie to Storrs (Connecticut) | 86.42 mi (139.08 km) |
| Poughkeepsie to Stoughton (Wisconsin) | 785.33 mi (1,263.87 km) |
| Poughkeepsie to Stow (Ohio) | 390.70 mi (628.77 km) |
| Poughkeepsie to Streamwood (Illinois) | 733.16 mi (1,179.91 km) |
| Poughkeepsie to Streator (Illinois) | 772.60 mi (1,243.38 km) |
| Poughkeepsie to Streetsboro (Ohio) | 385.56 mi (620.50 km) |
| Poughkeepsie to Strongsville (Ohio) | 410.02 mi (659.86 km) |
| Poughkeepsie to Stuart (Florida) | 1,063.80 mi (1,712.03 km) |
| Poughkeepsie to Stuarts Draft (Virginia) | 371.48 mi (597.84 km) |
| Poughkeepsie to Sturgis (Michigan) | 592.29 mi (953.19 km) |
| Poughkeepsie to Suamico (Wisconsin) | 740.25 mi (1,191.31 km) |
| Poughkeepsie to Sudley (Virginia) | 275.44 mi (443.29 km) |
| Poughkeepsie to Suffern (New York) | 41.76 mi (67.21 km) |
| Poughkeepsie to Suffolk (Virginia) | 374.81 mi (603.20 km) |
