| Poughkeepsie to Superior (Colorado) | 1,629.04 mi (2,621.69 km) |
| Poughkeepsie to Superior (Wisconsin) | 960.96 mi (1,546.52 km) |
| Poughkeepsie to Surprise (Arizona) | 2,158.85 mi (3,474.33 km) |
| Poughkeepsie to Susanville (California) | 2,404.03 mi (3,868.92 km) |
| Poughkeepsie to Sussex (Wisconsin) | 735.35 mi (1,183.43 km) |
| Poughkeepsie to Suwanee (Georgia) | 763.99 mi (1,229.52 km) |
| Poughkeepsie to Swansea (Illinois) | 874.67 mi (1,407.64 km) |
| Poughkeepsie to Sweetwater (Florida) | 1,159.67 mi (1,866.30 km) |
| Poughkeepsie to Sweetwater (Texas) | 1,584.79 mi (2,550.48 km) |
| Poughkeepsie to Sycamore (Illinois) | 759.11 mi (1,221.66 km) |
| Poughkeepsie to Sylacauga (Alabama) | 895.31 mi (1,440.87 km) |
| Poughkeepsie to Sylvania (Ohio) | 504.65 mi (812.16 km) |
| Poughkeepsie to Syosset (New York) | 64.54 mi (103.86 km) |
| Poughkeepsie to Syracuse (New York) | 146.68 mi (236.06 km) |
| Poughkeepsie to Syracuse (Utah) | 1,961.54 mi (3,156.79 km) |
