| Poughkeepsie to University Place (Washington) | 2,388.68 mi (3,844.21 km) |
| Poughkeepsie to Upland (California) | 2,414.35 mi (3,885.52 km) |
| Poughkeepsie to Upper Arlington (Ohio) | 491.52 mi (791.03 km) |
| Poughkeepsie to Upper Grand Lagoon (Florida) | 1,033.02 mi (1,662.48 km) |
| Poughkeepsie to Upper Montclair (New Jersey) | 60.61 mi (97.54 km) |
| Poughkeepsie to Urbana (Illinois) | 752.63 mi (1,211.24 km) |
| Poughkeepsie to Urbana (Maryland) | 242.98 mi (391.04 km) |
| Poughkeepsie to Urbana (Ohio) | 524.76 mi (844.52 km) |
| Poughkeepsie to Urbandale (Iowa) | 1,022.79 mi (1,646.02 km) |
| Poughkeepsie to Utica (New York) | 117.50 mi (189.10 km) |
| Poughkeepsie to Uvalde (Texas) | 1,681.63 mi (2,706.33 km) |
| Poughkeepsie to Vacaville (California) | 2,519.45 mi (4,054.67 km) |
| Poughkeepsie to Vadnais Heights (Minnesota) | 987.02 mi (1,588.45 km) |
| Poughkeepsie to Vail (Arizona) | 2,121.50 mi (3,414.22 km) |
| Poughkeepsie to Valdosta (Georgia) | 911.50 mi (1,466.91 km) |
