| Povoa de Santa Iria to Sestu | 972.87 mi (1,565.69 km) |
| Povoa de Santa Iria to Settimo Torinese | 964.42 mi (1,552.08 km) |
| Povoa de Santa Iria to Seveso | 1,039.07 mi (1,672.23 km) |
| Povoa de Santa Iria to Sezze | 1,179.29 mi (1,897.89 km) |
| Povoa de Santa Iria to Siano | 1,264.05 mi (2,034.29 km) |
| Povoa de Santa Iria to Siena | 1,102.86 mi (1,774.88 km) |
| Povoa de Santa Iria to Signa | 1,097.13 mi (1,765.67 km) |
| Povoa de Santa Iria to Silea | 1,184.42 mi (1,906.15 km) |
| Povoa de Santa Iria to Silvi Paese | 1,236.71 mi (1,990.29 km) |
| Povoa de Santa Iria to Sinalunga | 1,121.76 mi (1,805.30 km) |
| Povoa de Santa Iria to Siniscola | 1,002.37 mi (1,613.16 km) |
| Povoa de Santa Iria to Sinnai | 978.80 mi (1,575.22 km) |
| Povoa de Santa Iria to Siracusa | 1,328.56 mi (2,138.10 km) |
| Povoa de Santa Iria to Solaro | 1,035.97 mi (1,667.23 km) |
| Povoa de Santa Iria to Soliera | 1,103.35 mi (1,775.67 km) |
