| Prague to Sangeorz-Bai | 503.31 mi (810.00 km) |
| Prague to Sannicolau Mare | 398.48 mi (641.28 km) |
| Prague to Santana | 415.48 mi (668.65 km) |
| Prague to Satu Mare | 415.54 mi (668.74 km) |
| Prague to Scobinti | 599.14 mi (964.22 km) |
| Prague to Scornicesti | 607.63 mi (977.89 km) |
| Prague to Sebes | 509.40 mi (819.80 km) |
| Prague to Seini | 433.37 mi (697.44 km) |
| Prague to Sfantu-Gheorghe | 600.40 mi (966.25 km) |
| Prague to Sibiu | 538.69 mi (866.94 km) |
| Prague to Sighetu Marmatiei | 454.05 mi (730.72 km) |
| Prague to Sighisoara | 547.03 mi (880.37 km) |
| Prague to Simeria | 493.03 mi (793.45 km) |
| Prague to Sinaia | 611.27 mi (983.74 km) |
| Prague to Slatina | 607.54 mi (977.75 km) |
