| Progress to Southern Pines (North Carolina) | 379.00 mi (609.93 km) |
| Progress to Southfield (Michigan) | 365.42 mi (588.09 km) |
| Progress to Southgate (Michigan) | 356.08 mi (573.06 km) |
| Progress to Southlake (Texas) | 1,231.29 mi (1,981.57 km) |
| Progress to Spanaway (Washington) | 2,291.47 mi (3,687.76 km) |
| Progress to Spanish Fork (Utah) | 1,824.61 mi (2,936.42 km) |
| Progress to Spanish Lake (Missouri) | 719.12 mi (1,157.31 km) |
| Progress to Spanish Springs (Nevada) | 2,245.74 mi (3,614.17 km) |
| Progress to Sparks (Nevada) | 2,249.65 mi (3,620.47 km) |
| Progress to Spartanburg (South Carolina) | 462.31 mi (744.01 km) |
| Progress to Spearfish (South Dakota) | 1,400.08 mi (2,253.21 km) |
| Progress to Speedway (Indiana) | 498.63 mi (802.46 km) |
| Progress to Spencer (Iowa) | 962.83 mi (1,549.53 km) |
| Progress to Spokane (Washington) | 2,056.30 mi (3,309.30 km) |
| Progress to Spokane Valley (Washington) | 2,047.07 mi (3,294.45 km) |
