| Ptolemaida to Settimo Torinese | 772.66 mi (1,243.47 km) |
| Ptolemaida to Seveso | 724.31 mi (1,165.66 km) |
| Ptolemaida to Sezze | 454.17 mi (730.91 km) |
| Ptolemaida to Siano | 366.75 mi (590.23 km) |
| Ptolemaida to Siena | 565.85 mi (910.66 km) |
| Ptolemaida to Signa | 586.68 mi (944.17 km) |
| Ptolemaida to Silea | 591.27 mi (951.55 km) |
| Ptolemaida to Silvi Paese | 415.62 mi (668.88 km) |
| Ptolemaida to Sinalunga | 544.47 mi (876.24 km) |
| Ptolemaida to Siniscola | 628.88 mi (1,012.09 km) |
| Ptolemaida to Sinnai | 666.16 mi (1,072.08 km) |
| Ptolemaida to Siracusa | 418.59 mi (673.65 km) |
| Ptolemaida to Solaro | 725.83 mi (1,168.12 km) |
| Ptolemaida to Soliera | 619.14 mi (996.41 km) |
| Ptolemaida to Solofra | 358.65 mi (577.20 km) |
