| Ptolemaida to Somma Lombardo | 744.68 mi (1,198.44 km) |
| Ptolemaida to Somma Vesuviana | 380.30 mi (612.03 km) |
| Ptolemaida to Sommacampagna | 642.53 mi (1,034.06 km) |
| Ptolemaida to Sona | 644.33 mi (1,036.94 km) |
| Ptolemaida to Sondrio | 709.42 mi (1,141.70 km) |
| Ptolemaida to Sora | 427.83 mi (688.52 km) |
| Ptolemaida to Sorbolo | 643.50 mi (1,035.61 km) |
| Ptolemaida to Soresina | 682.31 mi (1,098.07 km) |
| Ptolemaida to Sorisole | 704.54 mi (1,133.85 km) |
| Ptolemaida to Sorrento | 383.60 mi (617.34 km) |
| Ptolemaida to Sorso | 686.60 mi (1,104.97 km) |
| Ptolemaida to Sortino | 426.01 mi (685.60 km) |
| Ptolemaida to Soverato Marina | 301.15 mi (484.65 km) |
| Ptolemaida to Sovicille | 569.91 mi (917.19 km) |
| Ptolemaida to Spello | 494.58 mi (795.95 km) |
