| Ptolemaida to Spilamberto | 609.27 mi (980.53 km) |
| Ptolemaida to Spilimbergo | 587.50 mi (945.48 km) |
| Ptolemaida to Spinea | 590.73 mi (950.69 km) |
| Ptolemaida to Spoleto | 489.43 mi (787.67 km) |
| Ptolemaida to Spoltore | 412.59 mi (664.01 km) |
| Ptolemaida to Spresiano | 598.09 mi (962.53 km) |
| Ptolemaida to Squinzano | 191.03 mi (307.44 km) |
| Ptolemaida to Statte | 235.40 mi (378.84 km) |
| Ptolemaida to Stezzano | 702.05 mi (1,129.83 km) |
| Ptolemaida to Strada | 572.01 mi (920.57 km) |
| Ptolemaida to Stradella | 701.58 mi (1,129.08 km) |
| Ptolemaida to Striano | 373.44 mi (600.99 km) |
| Ptolemaida to Subiaco | 456.45 mi (734.58 km) |
| Ptolemaida to Sulmona | 416.26 mi (669.90 km) |
| Ptolemaida to Surbo | 186.79 mi (300.61 km) |
