| Pueblo to Oskaloosa (Iowa) | 668.39 mi (1,075.66 km) |
| Pueblo to Oswego (Illinois) | 891.81 mi (1,435.23 km) |
| Pueblo to Oswego (New York) | 1,504.15 mi (2,420.70 km) |
| Pueblo to Otsego (Minnesota) | 743.43 mi (1,196.43 km) |
| Pueblo to Ottawa (Illinois) | 863.12 mi (1,389.05 km) |
| Pueblo to Ottawa (Kansas) | 506.21 mi (814.67 km) |
| Pueblo to Ottumwa (Iowa) | 675.27 mi (1,086.75 km) |
| Pueblo to Overland (Missouri) | 770.10 mi (1,239.36 km) |
| Pueblo to Overland Park (Kansas) | 537.48 mi (864.99 km) |
| Pueblo to Overlea (Maryland) | 1,508.20 mi (2,427.22 km) |
| Pueblo to Oviedo (Florida) | 1,498.77 mi (2,412.04 km) |
| Pueblo to Owasso (Oklahoma) | 501.54 mi (807.15 km) |
| Pueblo to Owatonna (Minnesota) | 714.49 mi (1,149.86 km) |
| Pueblo to Owensboro (Kentucky) | 951.55 mi (1,531.38 km) |
| Pueblo to Owings Mills (Maryland) | 1,493.32 mi (2,403.27 km) |
