| Pueblo to Scottsboro (Alabama) | 1,059.54 mi (1,705.16 km) |
| Pueblo to Scottsdale (Arizona) | 514.25 mi (827.61 km) |
| Pueblo to Scranton (Pennsylvania) | 1,543.62 mi (2,484.21 km) |
| Pueblo to Seabrook (Maryland) | 1,493.51 mi (2,403.57 km) |
| Pueblo to Seabrook (Texas) | 813.33 mi (1,308.93 km) |
| Pueblo to Seaford (New York) | 1,659.38 mi (2,670.51 km) |
| Pueblo to Seagoville (Texas) | 596.77 mi (960.41 km) |
| Pueblo to Seal Beach (California) | 813.39 mi (1,309.02 km) |
| Pueblo to Searcy (Arkansas) | 742.14 mi (1,194.36 km) |
| Pueblo to Seaside (California) | 949.41 mi (1,527.93 km) |
| Pueblo to SeaTac (Washington) | 1,093.26 mi (1,759.43 km) |
| Pueblo to Seattle (Washington) | 1,100.27 mi (1,770.72 km) |
| Pueblo to Sebastian (Florida) | 1,567.76 mi (2,523.07 km) |
| Pueblo to Sebring (Florida) | 1,530.59 mi (2,463.24 km) |
| Pueblo to Secaucus (New Jersey) | 1,628.84 mi (2,621.37 km) |
