| Puerto de la Cruz to Orbetello | 1,826.10 mi (2,938.83 km) |
| Puerto de la Cruz to Oria | 2,102.04 mi (3,382.91 km) |
| Puerto de la Cruz to Oristano | 1,633.75 mi (2,629.26 km) |
| Puerto de la Cruz to Orta Nova | 2,018.92 mi (3,249.14 km) |
| Puerto de la Cruz to Orte | 1,882.00 mi (3,028.79 km) |
| Puerto de la Cruz to Ortona | 1,975.70 mi (3,179.58 km) |
| Puerto de la Cruz to Orvieto | 1,875.68 mi (3,018.61 km) |
| Puerto de la Cruz to Orzinuovi | 1,860.45 mi (2,994.11 km) |
| Puerto de la Cruz to Osimo | 1,959.80 mi (3,153.99 km) |
| Puerto de la Cruz to Ospitaletto | 1,871.69 mi (3,012.20 km) |
| Puerto de la Cruz to Ostuni | 2,103.07 mi (3,384.56 km) |
| Puerto de la Cruz to Ottaviano | 1,947.97 mi (3,134.95 km) |
| Puerto de la Cruz to Ovada | 1,779.68 mi (2,864.12 km) |
| Puerto de la Cruz to Ozieri | 1,671.30 mi (2,689.70 km) |
| Puerto de la Cruz to Paceco | 1,798.27 mi (2,894.04 km) |
