| Puerto de la Cruz to Selargius | 1,646.58 mi (2,649.91 km) |
| Puerto de la Cruz to Selvazzano Dentro | 1,938.62 mi (3,119.91 km) |
| Puerto de la Cruz to Senago | 1,833.61 mi (2,950.91 km) |
| Puerto de la Cruz to Senigallia | 1,953.61 mi (3,144.03 km) |
| Puerto de la Cruz to Seravezza | 1,827.13 mi (2,940.49 km) |
| Puerto de la Cruz to Seregno | 1,838.76 mi (2,959.21 km) |
| Puerto de la Cruz to Seriate | 1,861.41 mi (2,995.64 km) |
| Puerto de la Cruz to Sermoneta | 1,888.78 mi (3,039.71 km) |
| Puerto de la Cruz to Serramanna | 1,638.45 mi (2,636.83 km) |
| Puerto de la Cruz to Serravalle Pistoiese | 1,850.71 mi (2,978.43 km) |
| Puerto de la Cruz to Sessa Aurunca | 1,928.58 mi (3,103.75 km) |
| Puerto de la Cruz to Sesto Calende | 1,818.60 mi (2,926.76 km) |
| Puerto de la Cruz to Sesto Fiorentino | 1,865.14 mi (3,001.66 km) |
| Puerto de la Cruz to Sesto San Giovanni | 1,835.95 mi (2,954.67 km) |
| Puerto de la Cruz to Sestri Levante | 1,799.19 mi (2,895.51 km) |
