| Puerto de la Cruz to Ede | 1,992.61 mi (3,206.79 km) |
| Puerto de la Cruz to Eemnes | 1,990.62 mi (3,203.59 km) |
| Puerto de la Cruz to Eerbeek | 2,007.03 mi (3,230.01 km) |
| Puerto de la Cruz to Eersel | 1,947.30 mi (3,133.88 km) |
| Puerto de la Cruz to Eijsden | 1,931.10 mi (3,107.80 km) |
| Puerto de la Cruz to Eindhoven | 1,956.43 mi (3,148.58 km) |
| Puerto de la Cruz to Elburg | 2,018.00 mi (3,247.65 km) |
| Puerto de la Cruz to Emmeloord | 2,028.24 mi (3,264.14 km) |
| Puerto de la Cruz to Emmen | 2,065.16 mi (3,323.55 km) |
| Puerto de la Cruz to Enkhuizen | 2,014.98 mi (3,242.80 km) |
| Puerto de la Cruz to Enschede | 2,037.46 mi (3,278.97 km) |
| Puerto de la Cruz to Epe | 2,016.86 mi (3,245.82 km) |
| Puerto de la Cruz to Ermelo | 2,003.70 mi (3,224.65 km) |
| Puerto de la Cruz to Etten-Leur | 1,938.07 mi (3,119.02 km) |
| Puerto de la Cruz to Franeker | 2,047.13 mi (3,294.54 km) |
