| Puerto de la Cruz to Santander | 1,257.28 mi (2,023.40 km) |
| Puerto de la Cruz to Santany | 1,353.52 mi (2,178.29 km) |
| Puerto de la Cruz to Santiago de Compostela | 1,094.31 mi (1,761.13 km) |
| Puerto de la Cruz to Santiago del Teide | 18.13 mi (29.17 km) |
| Puerto de la Cruz to Santiponce | 870.36 mi (1,400.72 km) |
| Puerto de la Cruz to Santomera | 1,113.86 mi (1,792.58 km) |
| Puerto de la Cruz to Santona | 1,267.07 mi (2,039.15 km) |
| Puerto de la Cruz to Santurce-Antiguo | 1,274.90 mi (2,051.76 km) |
| Puerto de la Cruz to Sarria | 1,115.75 mi (1,795.63 km) |
| Puerto de la Cruz to Sauzal | 8.20 mi (13.20 km) |
| Puerto de la Cruz to Sedavi | 1,195.69 mi (1,924.27 km) |
| Puerto de la Cruz to Segorbe | 1,208.08 mi (1,944.22 km) |
| Puerto de la Cruz to Segovia | 1,114.93 mi (1,794.31 km) |
| Puerto de la Cruz to Senmanat | 1,390.45 mi (2,237.72 km) |
| Puerto de la Cruz to Sesena | 1,088.79 mi (1,752.23 km) |
