| Puerto de la Cruz to Sestao | 1,274.72 mi (2,051.47 km) |
| Puerto de la Cruz to Sevilla | 863.46 mi (1,389.60 km) |
| Puerto de la Cruz to Sevilla La Nueva | 1,088.22 mi (1,751.33 km) |
| Puerto de la Cruz to Silla | 1,192.01 mi (1,918.36 km) |
| Puerto de la Cruz to Silleda | 1,090.62 mi (1,755.19 km) |
| Puerto de la Cruz to Sitges | 1,361.55 mi (2,191.20 km) |
| Puerto de la Cruz to Socuellamos | 1,087.38 mi (1,749.96 km) |
| Puerto de la Cruz to Soller | 1,347.28 mi (2,168.23 km) |
| Puerto de la Cruz to Solsona | 1,380.38 mi (2,221.51 km) |
| Puerto de la Cruz to Son Servera | 1,373.10 mi (2,209.79 km) |
| Puerto de la Cruz to Sonseca | 1,059.86 mi (1,705.69 km) |
| Puerto de la Cruz to Sopelana | 1,279.29 mi (2,058.82 km) |
| Puerto de la Cruz to Soria | 1,215.13 mi (1,955.56 km) |
| Puerto de la Cruz to Suances | 1,248.09 mi (2,008.61 km) |
| Puerto de la Cruz to Sueca | 1,190.22 mi (1,915.47 km) |
