| Royal Leamington Spa to Sacile | 768.48 mi (1,236.75 km) |
| Royal Leamington Spa to Sala Consilina | 1,153.37 mi (1,856.16 km) |
| Royal Leamington Spa to Salemi | 1,215.82 mi (1,956.68 km) |
| Royal Leamington Spa to Salerno | 1,110.69 mi (1,787.49 km) |
| Royal Leamington Spa to Salo | 715.18 mi (1,150.96 km) |
| Royal Leamington Spa to Salsomaggiore Terme | 736.13 mi (1,184.68 km) |
| Royal Leamington Spa to Saluzzo | 669.89 mi (1,078.08 km) |
| Royal Leamington Spa to Salzano | 774.10 mi (1,245.79 km) |
| Royal Leamington Spa to Samarate | 656.05 mi (1,055.81 km) |
| Royal Leamington Spa to San Benedetto del Tronto | 961.97 mi (1,548.14 km) |
| Royal Leamington Spa to San Biagio di Callalta | 776.66 mi (1,249.91 km) |
| Royal Leamington Spa to San Bonifacio | 750.83 mi (1,208.34 km) |
| Royal Leamington Spa to San Casciano in Val di Pesa | 835.72 mi (1,344.96 km) |
| Royal Leamington Spa to San Cataldo | 1,268.67 mi (2,041.73 km) |
| Royal Leamington Spa to San Cesareo | 986.09 mi (1,586.97 km) |
