| Royal Leamington Spa to Sestu | 1,030.99 mi (1,659.22 km) |
| Royal Leamington Spa to Settimo Torinese | 650.53 mi (1,046.93 km) |
| Royal Leamington Spa to Seveso | 666.15 mi (1,072.07 km) |
| Royal Leamington Spa to Sezze | 1,011.83 mi (1,628.38 km) |
| Royal Leamington Spa to Siano | 1,101.97 mi (1,773.45 km) |
| Royal Leamington Spa to Siena | 858.39 mi (1,381.45 km) |
| Royal Leamington Spa to Signa | 826.28 mi (1,329.77 km) |
| Royal Leamington Spa to Silea | 775.03 mi (1,247.29 km) |
| Royal Leamington Spa to Silvi Paese | 990.41 mi (1,593.91 km) |
| Royal Leamington Spa to Sinalunga | 876.67 mi (1,410.87 km) |
| Royal Leamington Spa to Siniscola | 967.89 mi (1,557.67 km) |
| Royal Leamington Spa to Sinnai | 1,033.41 mi (1,663.12 km) |
| Royal Leamington Spa to Siracusa | 1,330.85 mi (2,141.79 km) |
| Royal Leamington Spa to Solaro | 665.86 mi (1,071.59 km) |
| Royal Leamington Spa to Soliera | 771.17 mi (1,241.08 km) |
