| Runcorn to Sestu | 1,119.07 mi (1,800.97 km) |
| Runcorn to Settimo Torinese | 737.40 mi (1,186.73 km) |
| Runcorn to Seveso | 751.00 mi (1,208.61 km) |
| Runcorn to Sezze | 1,097.41 mi (1,766.11 km) |
| Runcorn to Siano | 1,186.77 mi (1,909.92 km) |
| Runcorn to Siena | 943.82 mi (1,518.93 km) |
| Runcorn to Signa | 911.43 mi (1,466.80 km) |
| Runcorn to Silea | 855.58 mi (1,376.92 km) |
| Runcorn to Silvi Paese | 1,073.92 mi (1,728.30 km) |
| Runcorn to Sinalunga | 961.83 mi (1,547.91 km) |
| Runcorn to Siniscola | 1,055.82 mi (1,699.17 km) |
| Runcorn to Sinnai | 1,121.49 mi (1,804.87 km) |
| Runcorn to Siracusa | 1,417.58 mi (2,281.37 km) |
| Runcorn to Solaro | 750.81 mi (1,208.31 km) |
| Runcorn to Soliera | 855.25 mi (1,376.39 km) |
