| Ruston to Southern Pines (North Carolina) | 780.45 mi (1,256.01 km) |
| Ruston to Southfield (Michigan) | 856.78 mi (1,378.85 km) |
| Ruston to Southgate (Michigan) | 844.26 mi (1,358.70 km) |
| Ruston to Southlake (Texas) | 263.92 mi (424.74 km) |
| Ruston to Spanaway (Washington) | 1,856.54 mi (2,987.81 km) |
| Ruston to Spanish Fork (Utah) | 1,177.04 mi (1,894.27 km) |
| Ruston to Spanish Lake (Missouri) | 453.16 mi (729.29 km) |
| Ruston to Spanish Springs (Nevada) | 1,580.41 mi (2,543.42 km) |
| Ruston to Sparks (Nevada) | 1,581.91 mi (2,545.83 km) |
| Ruston to Spartanburg (South Carolina) | 637.21 mi (1,025.50 km) |
| Ruston to Spearfish (South Dakota) | 1,021.58 mi (1,644.08 km) |
| Ruston to Speedway (Indiana) | 614.96 mi (989.68 km) |
| Ruston to Spencer (Iowa) | 746.00 mi (1,200.58 km) |
| Ruston to Spokane (Washington) | 1,663.84 mi (2,677.68 km) |
| Ruston to Spokane Valley (Washington) | 1,655.69 mi (2,664.58 km) |
