| Rye to Sacile | 638.70 mi (1,027.89 km) |
| Rye to Sala Consilina | 1,019.40 mi (1,640.57 km) |
| Rye to Salemi | 1,082.57 mi (1,742.23 km) |
| Rye to Salerno | 976.54 mi (1,571.59 km) |
| Rye to Salo | 582.14 mi (936.87 km) |
| Rye to Salsomaggiore Terme | 601.96 mi (968.76 km) |
| Rye to Saluzzo | 536.37 mi (863.20 km) |
| Rye to Salzano | 642.75 mi (1,034.41 km) |
| Rye to Samarate | 521.82 mi (839.78 km) |
| Rye to San Benedetto del Tronto | 828.69 mi (1,333.64 km) |
| Rye to San Biagio di Callalta | 646.01 mi (1,039.65 km) |
| Rye to San Bonifacio | 618.25 mi (994.98 km) |
| Rye to San Casciano in Val di Pesa | 701.49 mi (1,128.93 km) |
| Rye to San Cataldo | 1,134.86 mi (1,826.38 km) |
| Rye to San Cesareo | 851.77 mi (1,370.80 km) |
