| Sable-sur-Sarthe to Settimo Torinese | 428.07 mi (688.91 km) |
| Sable-sur-Sarthe to Seveso | 473.08 mi (761.35 km) |
| Sable-sur-Sarthe to Sezze | 789.15 mi (1,270.02 km) |
| Sable-sur-Sarthe to Siano | 885.49 mi (1,425.05 km) |
| Sable-sur-Sarthe to Siena | 643.92 mi (1,036.28 km) |
| Sable-sur-Sarthe to Signa | 617.05 mi (993.04 km) |
| Sable-sur-Sarthe to Silea | 615.98 mi (991.33 km) |
| Sable-sur-Sarthe to Silvi Paese | 791.15 mi (1,273.23 km) |
| Sable-sur-Sarthe to Sinalunga | 664.70 mi (1,069.73 km) |
| Sable-sur-Sarthe to Siniscola | 705.15 mi (1,134.83 km) |
| Sable-sur-Sarthe to Sinnai | 757.68 mi (1,219.36 km) |
| Sable-sur-Sarthe to Siracusa | 1,086.11 mi (1,747.93 km) |
| Sable-sur-Sarthe to Solaro | 471.43 mi (758.70 km) |
| Sable-sur-Sarthe to Soliera | 578.01 mi (930.22 km) |
| Sable-sur-Sarthe to Solofra | 890.57 mi (1,433.24 km) |
