| Saffle to Sestu | 1,380.76 mi (2,222.12 km) |
| Saffle to Settimo Torinese | 991.08 mi (1,594.99 km) |
| Saffle to Seveso | 945.32 mi (1,521.35 km) |
| Saffle to Sezze | 1,218.36 mi (1,960.76 km) |
| Saffle to Siano | 1,268.84 mi (2,042.00 km) |
| Saffle to Siena | 1,094.83 mi (1,761.95 km) |
| Saffle to Signa | 1,063.41 mi (1,711.40 km) |
| Saffle to Silea | 931.66 mi (1,499.36 km) |
| Saffle to Silvi Paese | 1,146.91 mi (1,845.78 km) |
| Saffle to Sinalunga | 1,100.91 mi (1,771.75 km) |
| Saffle to Siniscola | 1,290.01 mi (2,076.08 km) |
| Saffle to Sinnai | 1,379.95 mi (2,220.81 km) |
| Saffle to Siracusa | 1,528.12 mi (2,459.27 km) |
| Saffle to Solaro | 947.64 mi (1,525.08 km) |
| Saffle to Soliera | 998.17 mi (1,606.40 km) |
