| Saint-Sebastien-sur-Loire to Settimo Torinese | 465.72 mi (749.50 km) |
| Saint-Sebastien-sur-Loire to Seveso | 517.64 mi (833.07 km) |
| Saint-Sebastien-sur-Loire to Sezze | 818.85 mi (1,317.82 km) |
| Saint-Sebastien-sur-Loire to Siano | 916.01 mi (1,474.17 km) |
| Saint-Sebastien-sur-Loire to Siena | 678.44 mi (1,091.84 km) |
| Saint-Sebastien-sur-Loire to Signa | 653.64 mi (1,051.94 km) |
| Saint-Sebastien-sur-Loire to Silea | 664.87 mi (1,070.01 km) |
| Saint-Sebastien-sur-Loire to Silvi Paese | 827.76 mi (1,332.15 km) |
| Saint-Sebastien-sur-Loire to Sinalunga | 699.60 mi (1,125.89 km) |
| Saint-Sebastien-sur-Loire to Siniscola | 720.54 mi (1,159.59 km) |
| Saint-Sebastien-sur-Loire to Sinnai | 765.79 mi (1,232.41 km) |
| Saint-Sebastien-sur-Loire to Siracusa | 1,105.24 mi (1,778.71 km) |
| Saint-Sebastien-sur-Loire to Solaro | 515.70 mi (829.94 km) |
| Saint-Sebastien-sur-Loire to Soliera | 619.84 mi (997.54 km) |
| Saint-Sebastien-sur-Loire to Solofra | 921.55 mi (1,483.09 km) |
