| San Giovanni Rotondo to Settimo Torinese | 464.58 mi (747.67 km) |
| San Giovanni Rotondo to Seveso | 427.41 mi (687.85 km) |
| San Giovanni Rotondo to Sezze | 138.46 mi (222.83 km) |
| San Giovanni Rotondo to Siano | 82.20 mi (132.30 km) |
| San Giovanni Rotondo to Siena | 250.49 mi (403.13 km) |
| San Giovanni Rotondo to Signa | 275.61 mi (443.55 km) |
| San Giovanni Rotondo to Silea | 322.65 mi (519.26 km) |
| San Giovanni Rotondo to Silvi Paese | 101.55 mi (163.42 km) |
| San Giovanni Rotondo to Sinalunga | 229.22 mi (368.89 km) |
| San Giovanni Rotondo to Siniscola | 323.55 mi (520.71 km) |
| San Giovanni Rotondo to Sinnai | 380.84 mi (612.90 km) |
| San Giovanni Rotondo to Siracusa | 320.84 mi (516.34 km) |
| San Giovanni Rotondo to Solaro | 428.29 mi (689.27 km) |
| San Giovanni Rotondo to Soliera | 320.35 mi (515.55 km) |
| San Giovanni Rotondo to Solofra | 75.43 mi (121.40 km) |
