| San Giovanni Rotondo to Spilamberto | 307.99 mi (495.65 km) |
| San Giovanni Rotondo to Spilimbergo | 337.14 mi (542.58 km) |
| San Giovanni Rotondo to Spinea | 317.17 mi (510.43 km) |
| San Giovanni Rotondo to Spoleto | 172.16 mi (277.06 km) |
| San Giovanni Rotondo to Spoltore | 96.94 mi (156.02 km) |
| San Giovanni Rotondo to Spresiano | 331.33 mi (533.22 km) |
| San Giovanni Rotondo to Squinzano | 149.07 mi (239.90 km) |
| San Giovanni Rotondo to Statte | 109.35 mi (175.97 km) |
| San Giovanni Rotondo to Stezzano | 408.25 mi (657.01 km) |
| San Giovanni Rotondo to Strada | 259.41 mi (417.48 km) |
| San Giovanni Rotondo to Stradella | 398.52 mi (641.35 km) |
| San Giovanni Rotondo to Striano | 86.00 mi (138.40 km) |
| San Giovanni Rotondo to Subiaco | 136.55 mi (219.75 km) |
| San Giovanni Rotondo to Sulmona | 96.03 mi (154.54 km) |
| San Giovanni Rotondo to Surbo | 153.96 mi (247.77 km) |
