| San Giovanni Rotondo to Sangeorz-Bai | 588.92 mi (947.77 km) |
| San Giovanni Rotondo to Sannicolau Mare | 387.06 mi (622.92 km) |
| San Giovanni Rotondo to Santana | 430.23 mi (692.39 km) |
| San Giovanni Rotondo to Satu Mare | 547.59 mi (881.27 km) |
| San Giovanni Rotondo to Scobinti | 675.98 mi (1,087.89 km) |
| San Giovanni Rotondo to Scornicesti | 486.42 mi (782.82 km) |
| San Giovanni Rotondo to Sebes | 488.70 mi (786.49 km) |
| San Giovanni Rotondo to Seini | 558.08 mi (898.14 km) |
| San Giovanni Rotondo to Sfantu-Gheorghe | 577.56 mi (929.50 km) |
| San Giovanni Rotondo to Sibiu | 506.07 mi (814.44 km) |
| San Giovanni Rotondo to Sighetu Marmatiei | 586.84 mi (944.43 km) |
| San Giovanni Rotondo to Sighisoara | 547.49 mi (881.10 km) |
| San Giovanni Rotondo to Simeria | 462.29 mi (743.98 km) |
| San Giovanni Rotondo to Sinaia | 552.22 mi (888.71 km) |
| San Giovanni Rotondo to Slatina | 474.43 mi (763.52 km) |
