| San Lorenzo de Descardazar to Sestu | 310.46 mi (499.63 km) |
| San Lorenzo de Descardazar to Settimo Torinese | 444.82 mi (715.87 km) |
| San Lorenzo de Descardazar to Seveso | 511.88 mi (823.79 km) |
| San Lorenzo de Descardazar to Sezze | 529.52 mi (852.18 km) |
| San Lorenzo de Descardazar to Siano | 607.22 mi (977.23 km) |
| San Lorenzo de Descardazar to Siena | 488.79 mi (786.63 km) |
| San Lorenzo de Descardazar to Signa | 495.35 mi (797.19 km) |
| San Lorenzo de Descardazar to Silea | 619.22 mi (996.54 km) |
| San Lorenzo de Descardazar to Silvi Paese | 599.07 mi (964.12 km) |
| San Lorenzo de Descardazar to Sinalunga | 503.39 mi (810.12 km) |
| San Lorenzo de Descardazar to Siniscola | 345.29 mi (555.68 km) |
| San Lorenzo de Descardazar to Sinnai | 316.35 mi (509.12 km) |
| San Lorenzo de Descardazar to Siracusa | 673.11 mi (1,083.26 km) |
| San Lorenzo de Descardazar to Solaro | 508.75 mi (818.76 km) |
| San Lorenzo de Descardazar to Soliera | 527.40 mi (848.77 km) |
