| San Lorenzo de El Escorial to Southern Pines (North Carolina) | 3,993.54 mi (6,426.98 km) |
| San Lorenzo de El Escorial to Southfield (Michigan) | 3,935.97 mi (6,334.33 km) |
| San Lorenzo de El Escorial to Southgate (Michigan) | 3,942.08 mi (6,344.17 km) |
| San Lorenzo de El Escorial to Southlake (Texas) | 4,926.71 mi (7,928.77 km) |
| San Lorenzo de El Escorial to Spanaway (Washington) | 5,292.62 mi (8,517.65 km) |
| San Lorenzo de El Escorial to Spanish Fork (Utah) | 5,240.17 mi (8,433.23 km) |
| San Lorenzo de El Escorial to Spanish Lake (Missouri) | 4,378.38 mi (7,046.33 km) |
| San Lorenzo de El Escorial to Spanish Springs (Nevada) | 5,568.87 mi (8,962.23 km) |
| San Lorenzo de El Escorial to Sparks (Nevada) | 5,574.73 mi (8,971.67 km) |
| San Lorenzo de El Escorial to Spartanburg (South Carolina) | 4,125.34 mi (6,639.09 km) |
| San Lorenzo de El Escorial to Spearfish (South Dakota) | 4,739.33 mi (7,627.22 km) |
| San Lorenzo de El Escorial to Speedway (Indiana) | 4,161.14 mi (6,696.71 km) |
| San Lorenzo de El Escorial to Spencer (Iowa) | 4,435.86 mi (7,138.82 km) |
| San Lorenzo de El Escorial to Spokane (Washington) | 5,099.76 mi (8,207.26 km) |
| San Lorenzo de El Escorial to Spokane Valley (Washington) | 5,093.26 mi (8,196.81 km) |
