| San Luis Obispo to Portland (Oregon) | 717.15 mi (1,154.14 km) |
| San Luis Obispo to Seattle (Washington) | 857.83 mi (1,380.55 km) |
| San Luis Obispo to Denver (Colorado) | 918.04 mi (1,477.44 km) |
| San Luis Obispo to Dallas (Texas) | 1,375.92 mi (2,214.32 km) |
| San Luis Obispo to Houston (Texas) | 1,516.03 mi (2,439.82 km) |
| San Luis Obispo to Minneapolis (Minnesota) | 1,585.15 mi (2,551.05 km) |
| San Luis Obispo to St. Louis (Missouri) | 1,688.09 mi (2,716.72 km) |
| San Luis Obispo to Chicago (Illinois) | 1,826.87 mi (2,940.07 km) |
| San Luis Obispo to Los Angeles (California) | 151.19 mi (243.32 km) |
| San Luis Obispo to Atlanta (Georgia) | 2,054.74 mi (3,306.79 km) |
| San Luis Obispo to Detroit (Michigan) | 2,063.14 mi (3,320.30 km) |
| San Luis Obispo to Tampa (Florida) | 2,289.42 mi (3,684.47 km) |
| San Luis Obispo to Washington (District of Columbia) | 2,396.25 mi (3,856.40 km) |
| San Luis Obispo to Baltimore (Maryland) | 2,413.89 mi (3,884.78 km) |
| San Luis Obispo to Miami (Florida) | 2,477.14 mi (3,986.57 km) |
| San Luis Obispo to San Francisco (California) | 198.23 mi (319.02 km) |
| San Luis Obispo to Riverside (California) | 207.59 mi (334.09 km) |
| San Luis Obispo to Philadelphia (Pennsylvania) | 2,485.73 mi (4,000.39 km) |
| San Luis Obispo to Brooklyn (New York) | 2,542.08 mi (4,091.09 km) |
| San Luis Obispo to New York (New York) | 2,543.00 mi (4,092.56 km) |
| San Luis Obispo to Queens (New York) | 2,549.15 mi (4,102.45 km) |
| San Luis Obispo to Boston (Massachusetts) | 2,675.79 mi (4,306.28 km) |
| San Luis Obispo to San Diego (California) | 263.68 mi (424.36 km) |
| San Luis Obispo to Las Vegas (Nevada) | 310.23 mi (499.26 km) |
| San Luis Obispo to Phoenix (Arizona) | 502.66 mi (808.95 km) |
