| San Marcos to Southern Pines (North Carolina) | 2,151.08 mi (3,461.83 km) |
| San Marcos to Southfield (Michigan) | 1,945.37 mi (3,130.78 km) |
| San Marcos to Southgate (Michigan) | 1,945.60 mi (3,131.15 km) |
| San Marcos to Southlake (Texas) | 1,158.03 mi (1,863.67 km) |
| San Marcos to Spanaway (Washington) | 1,003.21 mi (1,614.51 km) |
| San Marcos to Spanish Fork (Utah) | 571.04 mi (919.01 km) |
| San Marcos to Spanish Lake (Missouri) | 1,551.62 mi (2,497.09 km) |
| San Marcos to Spanish Springs (Nevada) | 471.44 mi (758.70 km) |
| San Marcos to Sparks (Nevada) | 466.75 mi (751.16 km) |
| San Marcos to Spartanburg (South Carolina) | 2,011.63 mi (3,237.41 km) |
| San Marcos to Spearfish (South Dakota) | 1,061.58 mi (1,708.45 km) |
| San Marcos to Speedway (Indiana) | 1,769.26 mi (2,847.35 km) |
| San Marcos to Spencer (Iowa) | 1,375.97 mi (2,214.41 km) |
| San Marcos to Spokane (Washington) | 1,004.16 mi (1,616.04 km) |
| San Marcos to Spokane Valley (Washington) | 1,003.76 mi (1,615.40 km) |
