| San Mateo to Enterprise (Nevada) | 406.16 mi (653.65 km) |
| San Mateo to Enumclaw (Washington) | 666.92 mi (1,073.31 km) |
| San Mateo to Ephrata (Pennsylvania) | 2,460.38 mi (3,959.60 km) |
| San Mateo to Erie (Colorado) | 944.28 mi (1,519.67 km) |
| San Mateo to Erie (Pennsylvania) | 2,240.07 mi (3,605.04 km) |
| San Mateo to Erlanger (Kentucky) | 2,033.91 mi (3,273.26 km) |
| San Mateo to Escanaba (Michigan) | 1,887.23 mi (3,037.20 km) |
| San Mateo to Escondido (California) | 424.54 mi (683.23 km) |
| San Mateo to Española (New Mexico) | 904.12 mi (1,455.04 km) |
| San Mateo to Essex (Maryland) | 2,458.81 mi (3,957.08 km) |
| San Mateo to Essex Junction (Vermont) | 2,569.28 mi (4,134.86 km) |
| San Mateo to Estelle (Louisiana) | 1,916.08 mi (3,083.63 km) |
| San Mateo to Estero (Florida) | 2,474.15 mi (3,981.76 km) |
| San Mateo to Euclid (Ohio) | 2,170.11 mi (3,492.45 km) |
| San Mateo to Eufaula (Alabama) | 2,131.66 mi (3,430.58 km) |
