| San Sebastian de los Reyes to Spello | 855.22 mi (1,376.34 km) |
| San Sebastian de los Reyes to Spilamberto | 793.31 mi (1,276.71 km) |
| San Sebastian de los Reyes to Spilimbergo | 912.63 mi (1,468.73 km) |
| San Sebastian de los Reyes to Spinea | 865.69 mi (1,393.19 km) |
| San Sebastian de los Reyes to Spoleto | 854.41 mi (1,375.04 km) |
| San Sebastian de los Reyes to Spoltore | 926.98 mi (1,491.83 km) |
| San Sebastian de los Reyes to Spresiano | 876.05 mi (1,409.87 km) |
| San Sebastian de los Reyes to Squinzano | 1,136.13 mi (1,828.43 km) |
| San Sebastian de los Reyes to Statte | 1,090.68 mi (1,755.28 km) |
| San Sebastian de los Reyes to Stezzano | 755.73 mi (1,216.22 km) |
| San Sebastian de los Reyes to Strada | 793.41 mi (1,276.87 km) |
| San Sebastian de los Reyes to Stradella | 725.11 mi (1,166.95 km) |
| San Sebastian de los Reyes to Striano | 951.69 mi (1,531.60 km) |
| San Sebastian de los Reyes to Subiaco | 872.84 mi (1,404.71 km) |
| San Sebastian de los Reyes to Sulmona | 915.36 mi (1,473.13 km) |
