| San Sebastiano al Vesuvio to Settimo Torinese | 446.44 mi (718.48 km) |
| San Sebastiano al Vesuvio to Seveso | 423.75 mi (681.96 km) |
| San Sebastiano al Vesuvio to Sezze | 81.82 mi (131.67 km) |
| San Sebastiano al Vesuvio to Siano | 17.27 mi (27.79 km) |
| San Sebastiano al Vesuvio to Siena | 231.72 mi (372.92 km) |
| San Sebastiano al Vesuvio to Signa | 263.40 mi (423.91 km) |
| San Sebastiano al Vesuvio to Silea | 349.00 mi (561.67 km) |
| San Sebastiano al Vesuvio to Silvi Paese | 119.31 mi (192.01 km) |
| San Sebastiano al Vesuvio to Sinalunga | 213.02 mi (342.82 km) |
| San Sebastiano al Vesuvio to Siniscola | 245.26 mi (394.70 km) |
| San Sebastiano al Vesuvio to Sinnai | 292.74 mi (471.12 km) |
| San Sebastiano al Vesuvio to Siracusa | 264.73 mi (426.05 km) |
| San Sebastiano al Vesuvio to Solaro | 423.94 mi (682.26 km) |
| San Sebastiano al Vesuvio to Soliera | 321.26 mi (517.02 km) |
| San Sebastiano al Vesuvio to Solofra | 25.27 mi (40.66 km) |
