| San Sebastiano al Vesuvio to Spilamberto | 307.03 mi (494.11 km) |
| San Sebastiano al Vesuvio to Spilimbergo | 373.28 mi (600.74 km) |
| San Sebastiano al Vesuvio to Spinea | 340.58 mi (548.11 km) |
| San Sebastiano al Vesuvio to Spoleto | 158.60 mi (255.24 km) |
| San Sebastiano al Vesuvio to Spoltore | 112.66 mi (181.31 km) |
| San Sebastiano al Vesuvio to Spresiano | 358.15 mi (576.39 km) |
| San Sebastiano al Vesuvio to Squinzano | 195.08 mi (313.96 km) |
| San Sebastiano al Vesuvio to Statte | 149.55 mi (240.67 km) |
| San Sebastiano al Vesuvio to Stezzano | 408.60 mi (657.57 km) |
| San Sebastiano al Vesuvio to Strada | 245.86 mi (395.68 km) |
| San Sebastiano al Vesuvio to Stradella | 389.54 mi (626.90 km) |
| San Sebastiano al Vesuvio to Striano | 10.52 mi (16.93 km) |
| San Sebastiano al Vesuvio to Subiaco | 100.44 mi (161.64 km) |
| San Sebastiano al Vesuvio to Sulmona | 86.97 mi (139.97 km) |
| San Sebastiano al Vesuvio to Surbo | 199.79 mi (321.53 km) |
