| San Sebastiano al Vesuvio to Scottsboro (Alabama) | 5,180.58 mi (8,337.33 km) |
| San Sebastiano al Vesuvio to Scottsdale (Arizona) | 6,255.75 mi (10,067.66 km) |
| San Sebastiano al Vesuvio to Scranton (Pennsylvania) | 4,449.41 mi (7,160.64 km) |
| San Sebastiano al Vesuvio to Seabrook (Maryland) | 4,594.39 mi (7,393.96 km) |
| San Sebastiano al Vesuvio to Seabrook (Texas) | 5,804.93 mi (9,342.13 km) |
| San Sebastiano al Vesuvio to Seaford (New York) | 4,381.47 mi (7,051.29 km) |
| San Sebastiano al Vesuvio to Seagoville (Texas) | 5,720.63 mi (9,206.46 km) |
| San Sebastiano al Vesuvio to Seal Beach (California) | 6,460.78 mi (10,397.62 km) |
| San Sebastiano al Vesuvio to Searcy (Arkansas) | 5,397.37 mi (8,686.23 km) |
| San Sebastiano al Vesuvio to Seaside (California) | 6,409.03 mi (10,314.33 km) |
| San Sebastiano al Vesuvio to SeaTac (Washington) | 5,784.21 mi (9,308.79 km) |
| San Sebastiano al Vesuvio to Seattle (Washington) | 5,774.43 mi (9,293.05 km) |
| San Sebastiano al Vesuvio to Sebastian (Florida) | 5,225.49 mi (8,409.61 km) |
| San Sebastiano al Vesuvio to Sebring (Florida) | 5,284.92 mi (8,505.26 km) |
| San Sebastiano al Vesuvio to Secaucus (New Jersey) | 4,402.65 mi (7,085.38 km) |
