| San Severo to Sacile | 328.12 mi (528.06 km) |
| San Severo to Sala Consilina | 90.22 mi (145.19 km) |
| San Severo to Salemi | 300.92 mi (484.29 km) |
| San Severo to Salerno | 77.14 mi (124.15 km) |
| San Severo to Salo | 362.48 mi (583.35 km) |
| San Severo to Salsomaggiore Terme | 346.70 mi (557.96 km) |
| San Severo to Saluzzo | 446.46 mi (718.52 km) |
| San Severo to Salzano | 311.33 mi (501.03 km) |
| San Severo to Samarate | 426.52 mi (686.42 km) |
| San Severo to San Benedetto del Tronto | 115.57 mi (186.00 km) |
| San Severo to San Biagio di Callalta | 313.78 mi (504.98 km) |
| San Severo to San Bonifacio | 327.93 mi (527.76 km) |
| San Severo to San Casciano in Val di Pesa | 252.44 mi (406.26 km) |
| San Severo to San Cataldo | 300.34 mi (483.35 km) |
| San Severo to San Cesareo | 133.20 mi (214.37 km) |
